The practice of apprenticeship by secondary school students is observed among some relatively few Nigerians to earn a living either now or later in the future. This looks parallel to the practical solution that is recently being proffered and employed in the name of entrepreneurship studies in higher educational institutions in order to ameliorate the problem of graduate employment. It is in the light of this that this study examined the relationship between apprenticeship and students' academic performance in public junior secondary schools in Ado-Odo/Ota local Government of Ogun State, Nigeria. The study sample consisted of 15 public schools selected from a population of 48 on a stratified random basis. Ten teachers were randomly selected and ten Junior Secondary 2 students were purposively selected from each sample school to participate in the study. The participants responded to separately designed, validated and reliably tested questionnaires (r = 0.87 and 0.91 respectively) for teachers and students to collects pertinent data on apprenticeship. The study also gathered data, through Records Observation, on the academic performance of students. The collected data were employed in the test of the research hypotheses. Results of the analyses indicate no significant relationship between apprenticeship and academic performance and, no significant difference in academic performance between students on apprenticeship and students not on apprenticeship, and between male and female students on apprenticeship. The study recommends, among others, more or practical activities than theoretical lessons in Basic Technology and other hands-on subjects such that at the end of the 3-year Junior Secondary School, students could be certified in a trade subject to practice and earn a living from it.