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DOI Prefix 10.20431 |
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ARC Journal of Dental Science
Volume-2 Issue-1, 2017, Page No: 5-6
Mucosal Manifestation of Lupus Erythematosus
Thiago de Almeida P N C1, Livia B L2, João Paulo S S3, Luiz Fernando B P4
1.Post-Doctoral Research fellow, Department of Occlusion, Fixed Prostheses, and Dental Materials, School of Dentistry, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais Brazil.
2.PhD Student, Department of Occlusion, Fixed Prostheses, and Dental Materials, School of Dentistry, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais Brazil.
3.Professor, School of Dentistry, University of Uberaba (UNIUBE), Uberaba, Minas Gerais, Brazil.
4.Program of Specific Care of Oral Diseases, Stomatology Diagnosis Unit, HC, Federal University of Uberlândia, Uberlândia, Minas Gerais, Brazil.
2.PhD Student, Department of Occlusion, Fixed Prostheses, and Dental Materials, School of Dentistry, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais Brazil.
3.Professor, School of Dentistry, University of Uberaba (UNIUBE), Uberaba, Minas Gerais, Brazil.
4.Program of Specific Care of Oral Diseases, Stomatology Diagnosis Unit, HC, Federal University of Uberlândia, Uberlândia, Minas Gerais, Brazil.
Citation : Thiago de Almeida P N C, Livia B L, João Paulo S S, Luiz Fernando B P. Mucosal Manifestation of Lupus Erythematosus ARC Journal of Dental Science. 2017;2(1):5-6.
Copyright : © 2017 Thiago de Almeida P N C. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Lupus Erythematosus is an autoimmune rheumatic disease characterized by the action of antibodies against a variety of antigens. A large spectrum of oral mucosal lesions can be found in the systemic and cutaneous forms of lupus erythematosus. The present article reports a 67-year-old woman with Lupus Erythematosus associated with oral mucosal lesions.
Keywords: Lupus Erythematosus; Oral Lesions; Autoimmune Disease.
1.Case Report
Lupus Erythematosus is a classic example of autoimmune rheumatic disease, characterized by the action of antibodies against a variety of auto antigens. Biett in1828 and Kaposi in 1872 first described lupus erythematosus. The presentation of this autoimmune rheumatic diseasecan vary from a simple skin rash to progressive multiorgan disease. A large spectrum of oral mucosal lesions can be found in the systemic and cutaneous forms of lupus erythematosus [1].Typical cases of oral lesions are clinically characterized by the presence of white papules, central erythema, a border zone of irradiating white striae and peripheral telengiectasia [2-4]. In this way, the objective of the present article is to present a case of Lupus Erythematosus associated with oral mucosal lesions.
A 67-year-old woman presented with burning mouth symptomatology for several months was reported to our Private Clinic. Past medical history reveals chronic cutaneous lupus erythematosus and hypertension. Extra oral examination, obviously pointed to skin lesions on the scalp which appeared as depigmented scarring alopecia (Panel A). She also had a hyperkeratotic papules in elbows (Panel B). Intra- oral avaliation shows multiples erythematous lesions with difuse reddish marginal areas, and central areas with epithelium desquamation (Panel C, D E). Generalized bleeding on probing was present. There were no periodontal pockets, furcation involvement, and mobility. Excisional biopsy was done under local anesthesia in the maxillary anterior region. Specimen was sent for histopathologic examination and confirms the clinical diagnosis. The patient was treated with systemic corticosteroids and total resolution of mucosal manifestations was achieved in 2 months. After one year follow up no recurrence was found.
Figure 1. A - Skin lesions on the scalp which appeared as depigmented scarring alopecia. B – Presence of hyperkeratotic papules in elbows. C, D, E - multiples erythematous lesions with difuse reddish marginal areas; and central areas with epithelium desquamation.
References
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