Insect pests have continually hampered the production and utilization of maize. One of the ways of tackling their menace is through the introduction of resistant varieties. However, screening of maize varieties for resistance to moths has been under investigated. In this study, resistance of seven maize varieties to the tropical warehouse moth, Ephestia cautella (Walker), was evaluated in the laboratory at a temperature of 31±2oC and relative humidity of 78±3%. The tested maize varieties were LNPC4-4F2, ACR88Pop, ACR89DMR, DMRSR F1, TZL Comp1, TZBR Comp2 and K9350. Twenty grammes of each variety was infested with five pairs of adult E. cautella and replicated four times. The parameters used for the evaluation of resistance were grain damage, weight loss, adult emergence and calculated susceptibility index (SI). The most resistant of all the tested varieties with no grain damage, weight loss nor adult emergence was DMRSR F1. Hence, this variety had a zero susceptibility index. The most susceptible variety to E. cautella having the highest percentage grain damage (46.06%), weight loss (3.91%), adult emergence (21.66) and susceptibility index (SI = 3.82) was ACR89DMR. The remaining varieties had SI values ranging between 1.8 to3.59. Since the highest susceptibility index obtained was less than 5, all the tested varieties were relatively resistant to E. cautella infestation to various degrees. However, there was significant positive correlation at 0.05 levels between the grain length and the susceptibility of the varieties to E. cautella.