Medicinal plants have been used since time immemorial for the treatment of various ailments ranging from fevers to all kinds of infections in health care delivery systems especially in developing worlds. This present study was aimed at evaluating antibacterial properties of Ficus abutilifolia and Asimina triloba on selected bacterial strains. The selected bacterial strainare Salmonella typhi ATCC23564, Staphylococcus aureus ATCC29213, Streptococcus pyogenes ATCC8668, Campylobacter jejuni, VRE ATCC2025 and Shigella dysenteriae. The result VRE ATCC2025 with 49±0.70 showed that S. typhi had highest diameter zone of inhibition (58±1.02mm) followed by the least S. dysenteriae (25±0.38mm) of F. abutilifolia extract but the bacteria were resistant to A. triloba ethanol extract . These results were compared to the diameter zone of inhibition of the standard drug which was significantly different. The study revealed that F. abutilifolia ethanol leaf extract possessed antibacterial properties against the bacterial strains as well as greater minimum inhibition concentration (MIC) and minimum bactericidal concentration (MBC). The study therefore showed that ethanol leaf extract of Ficus abutilifolia possessed anti-typhoid and antibacterial properties and justifies its use as an ethnomedicinal prescription in traditional medicine.