Myrianthus arboreus is a food and medicinal wild plant. It can be found in many forest countries in Africa. In order to domesticate this species, a study of characterization and germination of wild seeds was conducted at the University of Jean Lorougnon Guede. Three devices, two seed substrates and three treatments were tested. The results revealed that the device under shade house is the best device for seed germination of M. arboreus with a rate of 92.78%. Red sawdust promotes more seed germination of M. arboreus with an average of 87.78 ± 8.63%. Black soil proved to be the best substrate for the development of seedlings. The rate and germination period does not differ significantly depending on the applied treatments. For germination conservation, the seeds left in the fruit turn out to be the best storage method. M. arboreus can be domesticated from its seeds