The application of traditional medicine to veterinary medicine has been termed as ethno-veterinary medicine. It is mainly concerned with folk beliefs, knowledge, skills, methods and practices which are used in the healthcare of animals. The knowledge varies from region to region, and from community to community. In general, ethno-veterinary practices have been developed by trial and error and by actual experimentation. EVM comprises of traditional surgical techniques, traditional immunization, magico-religious practices, and the use of herbal medicines to treat livestock diseases. The majority of livestock raisers in Ethiopia are geographically removed from the sites of veterinary stations, and those that are closer to the sites may not afford the fees for services. The inadequate funding at the national level for the prevention and control of animal diseases adds to the burden, especially among pastoralists who live in the remote arid and semi-arid lowland parts of the country. Therefore, a reasonable solution would be to complement modern veterinary health care with traditional care. Ethno veterinary medicine often provides cheaper options than comparable western drugs, and the products are locally available and more easily accessible. In the face of these and other factors, there is increasing interest in the field of ethno veterinary research and development. This growing interest had been encouraged by the recognition of some efficacious EVM products. In EVM diseases are diagnosed by palpating, looking and smelling. Some of the plants documented during the current study are used elsewhere in Ethiopia to treat same/similar livestock diseases. These include Acacia nilotica (used to treat diarrhoea); Acalypha indica (used against anthrax), Aloe trichosantha (used against anthrax, Contagious caprine pleuropneumonia and contagious bovine pleuropneumonia), Balanites aegyptiaca (used against anthrax), Calotropis procera (used against blackleg) and Dobera glabra (used against tick infestation).