This study investigated the relationship between asset integrity safety and organisational health in the Nigerian Petroleum Industry. The research design adopted the cross sectional survey and utilized the nonprobability purposive sampling technique in selecting the sample of 130 managers that responded to the statistical questionnaire survey. The study employed the self-administered questionnaire to obtain primary data, while secondary data were collected from the Department of Petroleum Resources (DPR) and the HSE Departments of the sampled companies. The SPSS Version 20 was used in analysing the data. Results show that asset integrity safety (WSP) has a significant relationship with organisational health, as the null hypotheses were all rejected. Therefore, based on the findings, it is recommended that the sector/industry management should adhere more strictly to benchmarked HSE compliance injunctions for corporate business continuity and environmental sustainability.