This study aims to test the hypothesis, with the intention of confirming or strengthening the hypotheses that in turn can reinforce the theories becoming foundations. By this consideration, the researcher tries to examine the influence of leadership and work attitude toward job satisfaction and job performance of HR at Konawe Hospital in Southeast Sulawesi. The number of respondents in this study is 79 respondents with the status of civil servants. The study is conducted by survey method by distributing questionnaires to the respondents. The findings of analysis show that: (1) Leadership has a positive and significant influence toward job satisfaction, (2) a work attitude has a positive and significant influence toward job satisfaction, (3) A Job Satisfaction has a significant and positive influence toward employee performance, (4) Leadership has a positive and not significant influence toward employee performance, (5) Work Attitude has a positive and significant influence toward employee performance