Meta-ultramafic rocks from the Paleoproterozoic Nyong Series (SE Cameroon) were investigated in this study. The aim was to study the petrology and evaluate the platinum group elements (PGEs) potentials of these rocks. A layered sequence exposed on a cliff face was mapped. Samples from the various horizons were collected and subsequently analysed in the laboratory for their petrographic and whole rock chemical compositions (but only the results of major oxides, Ni, Cu, Au and PGEs are presented in this study). The major element composition of the samples, determined by X-ray fluorescence (XRF), indicate that the protolith is ultramafic in nature with SiO2 and MgO contents that range from 38.62 to 44.22 wt % and 21.56 to 35.21 wt %, respectively. Gold (Au), copper (Cu), nickel (Ni) and SPGEs contents in the samples range from 1.3 - 517.7 ppb, 0.69 - 50 ppm, 680 - 2622 ppm and 5 - 11 ppm respectively. The principal PGEs identified by a combination of Ni sulphide fire assay, ICP-MS and instrumental neutron activation analysis (INAA) in these rocks are iridium (Ir, < 1 to 7 ppb), palladium (Pd, 3 to 5 ppb) and platinum (Pt, < 3 to 8 ppb). The effect of alteration of the rocks has resulted in the low PGE concentration due to remobilization. It is also suggested that the rocks are PGE-depleted due to low degree of partial melting or depleted mantle source. It is however, not clear what the chemical composition of the layer beneath the studied samples is. Such data may be very useful in judging the PGE potential of the region.