Oral liquid therapeutic is the most compliable form of therapeutics and a need for neonates to geriatrics where palatability is prime index but sugar based preparation poses threat like drug resistance, decline in self defence and predisposes for erythrocyte toxicity due to persisting infection as compared to oral liquid preparation free of sugar which promote early onset of relief of presentation without any evident alteration in therapeutic absorption . Thus, to check recurrence, relapse, drug resistance and potentiate therapeutic efficacy without any alteration in self defence. Oral liquid preparation free of sugar is preferred either as therapeutics or adjuvant.