House Hold Remedies in Phosphide Poisoning
Dr. Avinash Shankar1*, Dr. Amresh Shankar2, Dr. Anuradha Shankar 3
Citation : Dr. Avinash Shankar, Dr. Amresh Shankar, Dr. Anuradha Shankar,House Hold Remedies in Phosphide Poisoning International Journal of Clinical Chemistry and Laboratory Medicine 2019, 5(1) : 29-36.
Phosphide poisoning is known worldwide, especially in developing countries like India. It is being consumed frequently and exclusively for suicidal purpose. Among phosphide cereal preservatives (Aluminium phosphide -CELPHOS) and rodenticide (Zinc phosphide) are used quite rampantly. Considering the lethal outcome in patients remained untreated for longer duration, a measure to restrict release and absorption of phosphine various house hold measure being used, but majority i.e. - use of mustard oil, soap water and salt solution to induce emesis result in corrosive gastritis and bleeding which facilitate increased release and absorption of phosphine in turn increases toxicity and lethal outcome. Thus an awareness cum health education campaign was launched in 16 gram panchayat head quarter of Warisaliganj block of Nawada district of Bihar and educated through audio visual system to use Egg albumin Or Ghreet after any incident of phosphide poisoning (Aluminium phosphide Or Zinc phosphide) as early as possible and transfer the patient to appropriate centre for proper treatment .
Material & Method: After this awareness program 1525 patients of phosphide consumption admitted at Centre for Critical Care, RA. Hospital& Research Centre, Warisaliganj (Nawada) Bihar were considered, interrogated, clinically examined, investigated and duly treated.
Result: Out of all 1525 cases 945 cases have used either Egg albumin Or Ghreet within 1-2 hours and admitted at our centre within 3 hours of consumption ,had complete recovery in 99.5% patient (941/945 )within 12 hours while other attending within same time and given similar treatment only 228(39.3%) survived after rigorous and vigil observation for 36 hours but with altered haematological ,hepatic, renal and neurological deficit .
Conclusion: Administration of Egg albumin Or Ghreet acting as physicochemical barrier restrict phosphide dissolution ,release and absorption of phosphine as phosphide is non miscible to both ,thus markedly improve therapeutic outcome .