Abstract

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RA an auto immune disorder causing degenerative joint lesion for which anti arthritic analgesics, steroid and DMARDs are commonly used with an aim to improve pain, decrease inflammation and improve quality of life. Pain of RA is of nociceptive type than neuropathic and cure remain an existing challenge.Thus in the present study 210 cases of non diabetic non hypertensive RA cases with poor to worse quality of life non responsive to conventional practiced therapeutics ,a treatment module constituting Self blood 2ml with Inj Betamethasone 4mg (1ml) intramuscular every 4th day , (Inj Calcium Sandoz (Calcium gluconate and Calcium lactobionate )10 ml intravenous slowly every 15th day , Inj Methyl cobalamine 1500mcg with Nicotinamide and pyridoxine 100mg each intravenous every week , Cap Vit D3Cap Neurovit 1 cap daily and Acceclofenac 200mgwith Rabiprazol 20mg SR capsule daily) shows excellent therapeutic response in all the cases. Self bloof intramuscular induces antibody aginst RA antigen resulting in immunosuppression and competitive inhibition of immune body formation restricting joint inflammation ,degenerative changes of the joint and facilitate better joint mobility and ultimately improve quality of life .

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