Abstract

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Acute diarrhea is considered 2nd killer during infancy as commonly prescribed ant diarrheal agent ,constitute a composite of antimicrobial agent and anti protozoal drug, poses various drug induced untoward effects either due to super infection or drug adversity.
Interaction between diarrheal disease and nutritional status are complex and synergistic and serious issues globally., as they affect thousands of millions of young children every year and causes >3 millions death of children < 5yrs in spite of intensive filed based diagnosis and treatment.
Thus a planned study with therapeutically established molecule Racecadotril (Acetorphan),an enkephalinase inhibitor antisecretory and anti diarrheal used as safe and effective therapeutics for dioarrhea in adult and children is evaluated in infants in dose of 1.5mg/kg at 8 hrly dosefor its therapeutic effect and safety profile 6 Infants taking Racecadotril as adjuvant orally ensures early change in consistency and frequency of lose motion without any drug adversity or disease’s consequent squeal.

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