UV Spectrophotometric Determination of Allopurinol and Benzbromarone in their Binary Mixture using Artificial Neural Networks and Genetic Algorithm- Artificial Neural Networks
Mohammad Wafaa I. Nassar1, Khalid Abdel-Salam M. Attia1, Ahmed Abdelhalim A. Mohamad1, Ragab Ahmad M. Said1, Rady Fathy A. Gaber1
Citation : Mohammad Wafaa I. Nassar,et.al, UV Spectrophotometric Determination of Allopurinol and Benzbromarone in their Binary Mixture using Artificial Neural Networks and Genetic Algorithm- Artificial Neural Networks International Journal of Advanced Research in Chemical Science 2018, 5(8) : 24-29
Chemometric assisted spectrophotometric models were suggested for the selective quantitative determination of allopurinol and benzbromarone without previous separation. Multivariate artificial neural networks and genetic algorithm artificial neural networks were developed. The proposed methods were validated and successfully applied for the determination of the drugs in their commercial preparation.