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  DOI Prefix   10.20431


 

International Journal of Advanced Research in Chemical Science
Volume-3 Issue-8, 2016, Page No: 15-23
DOI: http://dx.doi.org/10.20431/2349-0403.0308003

Phytochemical Analysis and Antimicrobial Activity of Hagenia Abyssinica

Tesfaye Wolde11*, Behailu Bizuayehu2,Tesfaye Hailemariam3, Kassahun Tiruha4

1.Department of biology, College of Natural and computational Science, Wolkite University, Wolkite, Ethiopia
2.Department of chemistry, College of Natural and computational Science, Wolkite University, Wolkite, Ethiopia
3.Department of statistics, College of Natural and computational Science, Wolkite University, Wolkite, Ethiopia


Citation : Tesfaye Wolde, Behailu Bizuayehu, Tesfaye Hailemariam, Kassahun Tiruha, Phytochemical Analysis and Antimicrobial Activity of Hagenia Abyssinica International Journal of Advanced Research in Chemical Science. 2016;3(8):15-23.

Abstract


Introduction: Ethiopian communities highly depend on local plants to safe and sound their survival and health. Local trees are subjugated and used intensively for medicinal uses.
Objective: The aim of the present study was to carried out phytochemical analysis of organic extract of Hagenia abyssinica and to find out antihelmentic property of Hagenia abyssinica.
Methods: Hagenia abyssinica female flower extracts was used for plant component analysis and for determination of antihelmentic activity. Earth worm (Pheretima posthuma) strains were used for experimental purpose. Disc diffusion method was used to assess the antibacterial effect of the extracts on micro-organisms.
Results: The phytochemical screening indicated the presence of flavonoids, tannins, steroid, alkaloid, saponins in all extracts. Antibacterial and antihelmentic activity of Ethanolic, Methanolic, Hexane and Petroleum Ether extract of Hagenia abyssinica female flowers was highly active against Adult earthworm (Pheritima posthuma) and active against Staphyloccoccus aureus and showed less activity against Salmonella typhi.
Conclusion: The present study finally demonstrates that Hagenia abyssinica is a good source of various phytochemical such as Saponins, Phlobathanins, Flavonoids, Anthraquinones, Phenols, Terpenoids, Alkaloids, Steroids, Glycosides, Tannins. The antibacterial activity Hagenia abyssinica was clearly shown by the present study against bacteria. All these preliminary reports affirm an in depth analysis of the usefulness of Hagenia abyssinica as miracle drug against various ailments.


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