Department of Pharmacy,GRD (PG) Institute of Management and Technology,Dehradun, (Uttarakhand), India
Abstract
Heterocyclic compounds have paying strong attention interest. Many different derivatives have been prepared and possess various type useful pharmacological activities. A lot of work has been done on five member heterocyclic triazole ring system. Different pharmacological activities of triazole ring and its derivatives have been observed. Triazole derivatives possess a wide range of pharmacological activities such as anticancer, anticonvulsant, antimicrobial, anti-inflammatory, antioxidant, antitubercular, antimalarial, antinociceptive etc. In triazole ring, substitution at 1,4 and 1,3 positions with more electronegative group will possess more active compounds. This review contains various antmalarial activities of triazole compounds and also the landmark for the new research towards this moiety.