Department of Chemistry Hemchandracharya North Gujarat University Patan, (Gujarat) India
Abstract
Dialkyldithiophosphate derivatives of macrocyclic complexes of Pb(II), having N
4S
4 potential donors, of the general formula, [Pb(L){S
2P(OR)
2}
2] where L=macrocyclic ligands L
1, L
2, L
3, L
4 and L
5; R= C
2H
5-, C
3H
7n or C
3H
7i have been synthesized from the reaction of [Pb(L)X
2](where X= Cl
-, NO
3- or CH
3COO
-ˉ) with sodium dialkyldithiophosphate in 1:2 molar ratios in THF. These complexes have been characterized by elemental analysis, molar conductance, molecular weight determinations, IR,
1H,
13C & -
31P NMR. Molecular weight determinations of these complexes indicate their monomeric nature. Octahedral structures have been proposed on the basis of IR,
1H,
13C &
31P NMR, in which four nitrogen atoms of the macrocyclic ring coordinate to the central lead ion square-planar geometry and each dithiophosphate moiety occupies the axial positions binding the central lead ion in a unidentate manner. The antimicrobial activities of these derivatives have been studied by screening them Aspergillus flavus, Fusarium oxysporum, Alternaria alternata and bacteria like Salmonella typhi and Bacillus subtili. Dialkyldithiophosphate derivatives were found to be more fungitoxic and antibacterial than their corresponding macrocylic complexes.