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DOI Prefix 10.20431 |
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International Journal of Advanced Research in Chemical Science
Volume-1 Issue-10, 2014, Page No:5-8
Studies on the Synthesis of Some Novel 2-[2-(4-Oxo-4-P-Tolyl-4-Thia-1,3,3a,5 Tetraaza-Cyclo-Penta [A] Naphthalen-2-Yl Sulphanyl) -2-Aryl-Ethyl]-2-Phenyl-2,3-Dihydro-6 Substituted/Unsubstituted Benzo[E] [1,3]Oxazin-4 Ones
Ridam Misra*1,Shradha Sinha3,Shailja Pandey4,V.K.Pandey2,Chandra Prabha Pandey5
1.Babu Banarasi Das Northen India Institute of Technology
2.Department of Chemistry, Lucknow University, Lucknow
3.Babu Banarasi Das University
2.Department of Chemistry, Lucknow University, Lucknow
3.Babu Banarasi Das University
Citation : Ridam Misra,et.al, Studies on the Synthesis of Some Novel 2-[2-(4-Oxo-4-P-Tolyl-4-Thia-1,3,3a,5 Tetraaza-Cyclo-Penta [A] Naphthalen-2-Yl Sulphanyl) -2-Aryl-Ethyl]-2-Phenyl-2,3-Dihydro-6 Substituted/Unsubstituted Benzo[E] [1,3]Oxazin-4 Ones International Journal of Advanced Research in Chemical Science. 2014;1(10):5-8.
Abstract
Anthranilic acid 1 on treatment with p-toluene sulphonyl chloride in pyridine yields 4-oxo-2p-tolyl-2-benzo[d][1,2,3]oxathiazin-4-one (2) which on reaction with thiosemi-carbazide in pyridine, on refluxing for 4 hrs affords 4-oxo-4p-tolyl-4-thia 1,3,3a,5-tetraaza cyclopenta[a]naphthalene-3-thione (3). Compound 3 and an ,-unsaturated carbonyl compound in dimethyl sulphoxide containing trimethylamine on heating gives 3-(4-Oxo-4-p-tolyl-4-thia-1,3,3a,5-tetra azacyclopenta[a]naphthalen-3-yl-sulphonyl)-1-phenyl-3-aryl-propan-1-ones (4) which on reaction with salicylamide/5-arylamido/ imidoalkyl salicylamide in glacial acetic acid gives 2-[2-(4-oxo-4p-tolyl-4-thia-1,3,3a,5 tetra azacyclopenta[a]-naphthalen-2yl-sulphanyl)-2-aryl-ethyl-2-phenyl-2,3-dihydro-6-substituted/unsubstituted benzo [e] [1,3] oxazin-4-ones 5.
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