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DOI Prefix 10.20431 |
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International Journal of Advanced Research in Chemical Science
Volume-1 Issue-1, 2014, Page No:70-86
Synthesis, Characterization & Antimicrobial Activities of Substituted 2, 5-Disubstituted Phenyl-6-Substituted Phenyl Sulfonamide/Azomethine/ Azo /Phenylthiourea-Pyrimidines
Meghasham N. Narule
Vidya Vikas Art, Commerce & Science College, Samudrapur, Dist-Wardha, Maharashtra, INDIA.
Citation : Meghasham N. Narule, Synthesis, Characterization & Antimicrobial Activities of Substituted 2,5-Disubstituted Phenyl-6-Substituted Phenyl Sulfonamide/Azomethine / Azo / Phenylthiourea-Pyrimidines International Journal of Advanced Research in Chemical Science. 2014;1(1):70-86.
Abstract
Synthesis of substituted 2, 5-Disubstituted phenyl-6-substituted phenyl sulfonamide-pyrimidines (2a-m), 2, 5-Disubstituted phenyl-6-substituted Azomethine-pyrimidines (3a-m), substituted 2, 5-Disubstituted phenyl-6-azo-pyrimidines (4a-m), substituted 2, 5-Disubstituted phenyl-6-N-phenylthiourea-pyrimidines (5a-m) from 2, 5-Disubstituted phenyl-6-amine-pyrimidines (1a-m) is reported in this paper. The structures of synthesized products have been characterized on the basis of FT-IR, 1HNMR, FAB-MS and elemental analysis. The title compounds are found to have antibacterial and antifungal activities.
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