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DOI Prefix 10.20431 |
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International Journal of Advanced Research in Chemical Science
Volume-1 Issue-1, 2014, Page No:28-47
Synthesis,Characterization &Pharmacological Activities of
Substituted-2-Methyl-7-Substituted-Sulphonomides/Azo/Schiff’s Bases/-N-Phenylthiourea-4-Quinolones
M. N. Narule,Tasneem K.H. Khan
1.HOD, Dept. of Chemistry, Vidya vikas Art, Commerce & Science College, Samudrapur, Wardha, India.
2.Anjuman Engineering college, Nagpur
2.Anjuman Engineering college, Nagpur
Citation : M. N. Narule,Tasneem K.H. Khan, Synthesis,Characterization &Pharmacological Activities of Substituted-2-Methyl-7-Substituted-Sulphonomides/Azo/Schiff's Bases/-N-Phenylthiourea-4-Quinolones International Journal of Advanced Research in Chemical Science. 2014;1(1):28-47.
Abstract
The synthesis and pharmacological activities of substituted -2-Methyl-7-substituted- sulphonomides-4-quinolones (2a-m), substituted -2-Methyl-7-substituted- azo -4-quinolones (3a- m), substituted -2-Methyl-7-substituted-Schiff bases -4-quinolones (4a-m), substituted -2-Methyl-7-substituted- N-phenylthiourea -4-quinolones (5a-m) respectively from substituted 2-Methyl-7-amino-4-quinolones (1a-m) is reported in this paper. The structures of synthesized products have been characterized on the basis of FT-IR, 1HNMR, FAB-MS and elemental analysis. The title compounds are found to have antibacterial and antifungal activities.
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