Antithrombotic therapy is the main therapy for acute deep vein thrombosis. The objectives of anticoagulant therapy in the initial treatment are to prevent thrombus extension and early and late recurrences of deep vein thrombosis and pulmonary embolism. The main objective of our study is to analyze the usage of low molecular weight heparins in women, during the period of pregnancy. Our study, represents a retrospective study, which was undertaken during 01 July - 31 December 2013, in the Department of Gynecology and Obstetrics, at Clinical Hospital in Tetova. Among of 817 pregnant women, 277 of them received anticoagulant therapy, respectively Low Molecular Weight Heparins. 119 of them were patients with risky pregnancy and 68 were with the diagnosis Hypercoagulable State