3D-AFM investigations introduce precize view on the nano-and microstructural properties of sulfonyl-urea as active moeity and link between suitability of sulfonyl urea as antidiabetic drug and its internal micro-structural features specially exposured surface area. The structural investigations are focusing on the parameters such as bond distances inside unit cell , torsion on angles and different oxidation states present together inside unit cell . All of theses structural prameters play an important role on the stability of this moeity as functionalized group which could be linked with many active groups .The visualization studies specially bond distances measurements indicated that there are three different types of N-H bonds .Furthermore visualized XRD pattern was constructed and the fingure print peaks of sulphoyl urea which lies at two theta ~25 with [200] muller index were compared and discussed in details taking into our account electronics inductive effects generated from neighboring surrounding function groups