The pharmacokinetic study of medicinal plants Hibiscus Rosa-sinenses-L (HRS) of malvaceae family in vitro condition have been carried out electrochemically using Ag-Zn pair of electrodes in vitro condition in three different seasons. The investigation shows first to zero order kinetics for complex oscillatory reactions occurring in the system at long span of time. The reaction velocity enhanced by charge transfer of Zwitter ions between biomass and electrodes. The measured activation parameters fully explained the suggested mechanism and activity.