Abstract

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The Staudinger reaction enables an easy access to sugar amide glycolipids including monoamide and bisamide at the anomeric positions by substitute the hydroxyl group after preparing the target hydroxyl group and protect the other hydroxyl groups. It’s possible to drive Staudinger reaction to cyclization reaction by control the solvent and the quantities of the reactants to produce tetrahydropyrimidine compounds instead of the double amide chains. This is considering as new methodology to synthesis tetrahydropyrimidine sugars. It is used to synthesis new sugar surfactants. Both bisamide and Tetrahydropyrimidine sugar are a new type of surfactants and are easily accessed as chemically pure compounds based from natural renewable resources e.g. sugar and fatty acids both are reasonable economic and environmental friendly.

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